medusa.reconstruct.degrade

Module Contents

medusa.reconstruct.degrade.degrade_reactions(base_model, num_reactions, num_models=10)

Removes reactions from an existing COBRA model to generate an ensemble.

Parameters:

• base_model (cobra.Model) – Model from which reactions will be removed to create an ensemble.
• num_reactions (int) – The number of reactions to remove to generate each ensemble member. Must be smaller than the total number of reactions in the model
• num_models (int) – The number of models to generate by randomly removing num_reactions from the base_model. Reactions are removed with replacement.

Returns:

An ensemble

Return type:

Medusa.core.ensemble